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Article

RUNX1 and REXO2 are associated with the heterogeneity and prognosis of IDH wild type lower grade glioma.

Scientific reports - 4 Jun 2021

Wang Haiwei, Wang Xinrui, Xu Liangpu, Zhang Ji, Cao Hua

Abstract excerpt

Based on isocitrate dehydrogenase (IDH) alterations, lower grade glioma (LGG) is divided into IDH mutant and wild type subgroups. However, the further classification of IDH wild type LGG was unclear. Here, IDH wild type LGG patients in The Cancer Genome Atlas and Chinese Glioma Genome Atlas were divided into two sub-clusters using non-negative matrix factorization. IDH wild type LGG patients in sub-cluster2 had...

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Identifiers

PMID: 34088969
DOI: 10.1038/s41598-021-91382-1
PMCID: PMC8178394

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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