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Identification of Iron Metabolism-Related Genes as Prognostic Indicators for Lower-Grade Glioma

9 Sept 2021

Abstract excerpt

Lower-grade glioma (LGG) is characterized by genetic and transcriptional heterogeneity, and a dismal prognosis. Iron metabolism is considered central for glioma tumorigenesis, tumor progression and tumor microenvironment, although key iron metabolism-related genes are unclear. Here we developed and validated an iron metabolism-related gene signature LGG prognosis. RNA-sequence and clinicopathological data from...

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Share to Epigenetics and DNA Methylation
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PMID: 34568059
DOI: 10.3389/fonc.2021.729103

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