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Article

Myoinositol to Total Choline Ratio in Glioblastomas as a Potential Prognostic Factor in Preoperative Magnetic Resonance Spectroscopy.

Neurologia medico-chirurgica - 15 Aug 2021

Kumon Masanobu, Nakae Shunsuke, Murayama Kazuhiro, Kato Takema, Ohba Shigeo, Inamasu Joji, Yamada Seiji, Abe Masato, Sasaki Hikaru, Ohno Yoshiharu, Hasegawa Mitsuhiro, Kurahashi Hiroki, Hirose Yuichi

Abstract excerpt

Isocitrate dehydrogenase (IDH) wild-type diffuse astrocytic tumors tend to be pathologically diagnosed as glioblastomas (GBMs). We previously reported that myoinositol to total choline (Ins/Cho) ratio in GBMs on magnetic resonance (MR) spectroscopy was significantly lower than that in IDH-mutant gliomas. We then hypothesized that a low Ins/Cho ratio is a poor prognosis factor in patients with GBMs, IDH-wild-type....

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Identifiers

PMID: 34078827
DOI: 10.2176/nmc.oa.2020-0312
PMCID: PMC8365238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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