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Article

Molecular subtyping of brain metastases and implications for therapy.

Current treatment options in oncology - 1 Dec 2013

Renfrow Jaclyn J, Lesser Glenn J

Abstract excerpt

OPINION STATEMENT: Molecular subtyping of tumors and treatment with specifically targeted therapy is a rapidly developing trend in oncology. Genetic and protein biomarkers impact biological behavior, patient prognosis, and inform treatment options. Select examples include EGFR mutations in primary non-small cell lung cancers, Her2 overexpression in breast cancer, and BRAF mutations in melanoma. Systemic benefit...

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Identifiers

PMID: 23907440
DOI: 10.1007/s11864-013-0248-2

Genes

BRAF
EGFR

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