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DNA Repair Gene Polymorphisms and Susceptibility to Urothelial Carcinoma in a Southeastern European Population.

Current oncology (Toronto, Ont.) - 14 May 2021

Samara Maria, Papathanassiou Maria, Mitrakas Lampros, Koukoulis George, Vlachostergios Panagiotis J, Tzortzis Vassilios

Abstract excerpt

Single nucleotide polymorphisms (SNPs) in DNA repair genes may predispose to urothelial carcinoma of the bladder (UCB). This study focused on three specific SNPs in a population with high exposure to environmental carcinogens including tobacco and alcohol. A case-control study design was used to assess for presence of XPC PAT +/-, XRCC3 Thr241Met, and ERCC2 Lys751Gln DNA repair gene SNPs in peripheral blood from...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34068981
DOI: 10.3390/curroncol28030174
PMCID: PMC8161783

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