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Article

Genetic variation in the nucleotide excision repair pathway and bladder cancer risk.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Mar 2006

García-Closas Montserrat, Malats Núria, Real Francisco X, Welch Robert, Kogevinas Manolis, Chatterjee Nilanjan, Pfeiffer Ruth, Silverman Debra, Dosemeci Mustafa, Tardón Adonina, Serra Consol, Carrato Alfredo, García-Closas Reina, Castaño-Vinyals Gemma, Chanock Stephen, Yeager Meredith, Rothman Nathaniel

Abstract excerpt

Nucleotide excision repair (NER) is critical for protecting against damage from carcinogens in tobacco smoke. We evaluated the influence of common genetic variation in the NER pathway on bladder cancer risk by analyzing 22 single nucleotide polymorphisms (SNP) in seven NER genes (XPC, RAD23B, ERCC1, ERCC2, ERCC4, ERCC5, and ERCC6). Our study population included 1,150 patients with transitional cell carcinoma of...

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Identifiers

PMID: 16537713
DOI: 10.1158/1055-9965.EPI-05-0749

Genes

ERCC1
ERCC2
ERCC5
ERCC4
ERCC6
XPC

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in the nucleotide excision repair pathway and bladder cancer risk.PMID 16537713Read ↗

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High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder cancer risk.Semantic proximity Read ↗

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