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Article

DNA repair gene ERCC2, XPC, XRCC1, XRCC3 polymorphisms and associations with bladder cancer risk in a French cohort.

Anticancer research - 1 Jan 2000

Fontana Luc, Bosviel Rémy, Delort Laetitia, Guy Laurent, Chalabi Nasséra, Kwiatkowski Fabrice, Satih Samir, Rabiau Nadège, Boiteux Jean-Paul, Chamoux Alain, Bignon Yves-Jean, Bernard-Gallon Dominique J

Abstract excerpt

In polygenic diseases, association studies look for genetic variation such as polymorphisms in low penetrance genes, i.e. genes in interaction with environmental factors. DNA repair systems that protect the genome from deleterious endogenous and exogenous damage have been shown to significantly reduce activity. In particular, enzymes of the nucleotide excision repair pathway are suspected to be implicated in...

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Identifiers

PMID: 18630471

Genes

XPC
ERCC2
XRCC1
XRCC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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