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Article

Genetic changes in plaque-purified varicella vaccine strain Suduvax during in vitro propagation in cell culture.

Journal of microbiology (Seoul, Korea) - 1 Jul 2021

Hwang Hye Rim, Kang Se Hwan, Lee Chan Hee

Abstract excerpt

Infection by varicella-zoster virus (VZV) can be prevented by using live attenuated vaccines. VZV vaccine strains are known to evolve rapidly in vivo, however, their genetic and biological effects are not known. In this study, the plaque-purified vaccine strain Suduvax (PPS) was used to understand the genetic changes that occur during the process of propagation in in vitro cell culture. Full genome sequences of...

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Share to Cell Line
Share to DNA, Viral
Share to Genome, Viral

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Herpesvirus 3, Human

Share to Polymorphism, Genetic

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Source

Identifiers

PMID: 34061341
DOI: 10.1007/s12275-021-1062-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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