Article
Rashes occurring after immunization with a mixture of viruses in the Oka vaccine are derived from single clones of virus.
The Journal of infectious diseases - 15 Aug 2004
Quinlivan Mark L, Gershon Anne A, Steinberg Sharon P, Breuer Judith
Abstract excerpt
Vaccination against chickenpox causes a varicella-like rash in up to 5% of healthy children and 50% of children with leukemia. The vaccine may establish latency and reactivate to cause herpes zoster, albeit more rarely than wild-type virus. All vaccine preparations are composed of a mixture of varicella-zoster virus strains that show genotypic variation at several loci. We have shown, by DNA sequencing of 40...
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