Article
Characterization of live-attenuated Japanese encephalitis vaccine virus SA14-14-2.
Vaccine - 13 May 2014
Yang Dong, Li Xiao-Feng, Ye Qing, Wang Hong-Jiang, Deng Yong-Qiang, Zhu Shun-Ya, Zhang Yu, Li Shi-Hua, Qin Cheng-Feng
Abstract excerpt
The live attenuated Japanese encephalitis (JE) vaccine SA14-14-2 was licensed decades ago and now approved for clinical use in most JE endemic countries. Large-scale clinical trials demonstrate ideal safety and efficacy profile of this Chinese vaccine. The SA14-14-2 vaccine was derived from a virulent strain SA14 after hundreds of serial passaging in cells and animals, concern about virulence reversion remains...
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