Article
Genetic profile of an Oka varicella vaccine virus variant isolated from an infant with zoster.
Journal of clinical microbiology - 1 Dec 2004
Sauerbrei Andreas, Rubtcova Elena, Wutzler Peter, Schmid D Scott, Loparev Vladimir N
Abstract excerpt
Varicella virus vaccine strain Oka (V-Oka) has in rare cases caused zoster in vaccinated people. Despite broad usage of V-Oka, little is known about varicella-zoster virus genomic sequence variation of strains in vaccine and isolates from patients with vaccine adverse events. Direct sequencing of 20 regions of V-Oka-GSK was compared to the sequences of the original V-Oka-Biken, GlaxoSmithKline Oka vaccine...
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