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Article

Analysis of single nucleotide polymorphism among Varicella-Zoster Virus and identification of vaccine-specific sites.

Virology - 1 Sept 2016

Jeon Jeong Seon, Won Youn Hee, Kim In Kyo, Ahn Jin Hyun, Shin Ok Sarah, Kim Jung Hwan, Lee Chan Hee

Abstract excerpt

Varicella-zoster virus (VZV) is a causative agent for chickenpox and zoster. Live attenuated vaccines have been developed based on Oka and MAV/06 strains. In order to understand the molecular mechanisms of attenuation, complete genome sequences of vaccine and wild-type strains were compared and single nucleotide polymorphism (SNP) was analyzed. ORF22 and ORF62 contained the highest number of SNPs. The detailed...

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Identifiers

PMID: 27376245
DOI: 10.1016/j.virol.2016.06.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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