Article
Increase in the genetic polymorphism of varicella-zoster virus after passaging in in vitro cell culture.
Journal of microbiology (Seoul, Korea) - 1 Nov 2019
Hwang Hye Rim, Kim Seok Cheon, Kang Se Hwan, Lee Chan Hee
Abstract excerpt
Primary infections with the varicella-zoster virus (VZV) result in varicella, while latent reactivation leads to herpes zoster. Both varicella and zoster can be prevented by live attenuated vaccines. There have been reports suggesting that both clinical VZV strains and those in vaccine preparations are genetically polymorphic, containing mixtures of both wild-type and vaccine-type sequences at certain...
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