Article
Association of mitotic regulation pathway polymorphisms with pancreatic cancer risk and outcome.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jan 2010
Couch Fergus J, Wang Xianshu, Bamlet William R, de Andrade Mariza, Petersen Gloria M, McWilliams Robert R
Abstract excerpt
BACKGROUND: Mitosis is a highly regulated process that serves to ensure the fidelity of cell division. The disruption of mitotic regulators leading to aneuploidy and polyploidy is commonly observed in cancer cells. Single nucleotide polymorphisms (SNP) in regulators of mitosis may promote chromos...
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