Article
Significance of KDM6A mutation in bladder cancer immune escape.
BMC cancer - 29 May 2021
Chen Xingxing, Lin Xuehua, Pang Guofu, Deng Jian, Xie Qun, Zhang Zhengrong
Abstract excerpt
BACKGROUND: Bladder cancer (BC) is the fourth most prevalent neoplasm in men and is associated with high tumour recurrence rates, leading to major treatment challenges. Lysine-specific demethylase 6A (KDM6A) is frequently mutated in several cancer types; however, its effects on tumour progression and clinical outcome in BC remain unclear. Here, we explored the potential role of KDM6A in regulating the antitumor...
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