Article
Multi-omics analysis of tumor mutation burden combined with immune infiltrates in bladder urothelial carcinoma.
Journal of cellular physiology - 1 Apr 2020
Zhang Chuanjie, Shen Luping, Qi Feng, Wang JinCheng, Luo Jun
Abstract excerpt
To explore the prognosis of tumor mutation burden (TMB) and underlying relationships with tumor-infiltrating immune cells in bladder cancer (BLCA). Transcriptome profiles and somatic mutation data from The Cancer Genome Atlas database by the GDC tool. A total of 437 samples were included, consisted of 412 BLCA patients and matched 25 normal samples. Specific mutation information was summarized and illustrated in...
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