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Integrative Analysis Reveals the Prognostic Effects of Epigenetic Regulators in Bladder Cancer

1 Jul 2025

Abstract excerpt

BACKGROUND: Epigenetic regulatory genes (epiRG) are pivotal in the epigenetic regulation of the human genome, primarily through DNA and histone modifications. These genes are frequently mutated in human cancers, particularly bladder cancer (BC). However, the functional impact of epiRG mutations on patient outcomes remains poorly understood. METHODS: In this study, we developed gene signatures for the most...

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Share to Bladder and Urothelial Cancer Treatments
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PMID: 40693457
DOI: 10.1002/cam4.71057

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