Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The healing myocardium mobilizes a distinct B-cell subset through a CXCL13-CXCR5-dependent mechanism.

Cardiovascular research - 22 Nov 2021

Heinrichs Margarete, Ashour DiyaaElDin, Siegel Johanna, Büchner Lotte, Wedekind Georg, Heinze Katrin G, Arampatzi Panagiota, Saliba Antoine-Emmanuel, Cochain Clement, Hofmann Ulrich, Frantz Stefan, Campos Ramos Gustavo

Abstract excerpt

AIMS: Recent studies have revealed that B cells and antibodies can influence inflammation and remodelling following a myocardial infarction (MI) and culminating in heart failure-but the mechanisms underlying these observations remain elusive. We therefore conducted in mice a deep phenotyping of the post-MI B-cell responses in infarcted hearts and mediastinal lymph nodes, which drain the myocardium. Thereby, we...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocyte Subsets
Share to Chemokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chemotaxis, Leukocyte

Share to Immunoglobulins

Share to Lymph Nodes

Share to RNA-Seq

Share to Single-Cell Analysis

Share to Transforming Growth Factor beta1

Source

Identifiers

PMID: 34048536
DOI: 10.1093/cvr/cvab181

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The healing myocardium mobilizes a distinct B-cell subset through a CXCL13-CXCR5-dependent mechanism.PMID 34048536Read ↗

Persistent transcriptional changes in cardiac adaptive immune cells following myocardial infarction: New evidence from the re-analysis of publicly available single cell and nuclei RNA-sequencing data setsSemantic proximity Read ↗

Rapid differentiation of regulatory CD4 <sup>+</sup> T cells in the infarcted myocardium blunts in situ inflammationSemantic proximity Read ↗

Myocardial Milieu Favors Local Differentiation of Regulatory T CellsSemantic proximity Read ↗

Prominin-1+/CD133+ bone marrow-derived heart-resident cells suppress experimental autoimmune myocarditis.Semantic proximity Read ↗

Dissecting antibody responses to cardiac receptors in patients with myocardial infarctionSemantic proximity Read ↗

Full Expression of Cardiomyopathy Is Partly Dependent on B-Cells: A Pathway That Involves Cytokine Activation, Immunoglobulin Deposition, and Activation of Apoptosis.Semantic proximity Read ↗

Lymphocytes at the Heart of Wound Healing.Semantic proximity Read ↗

VEGF-C-mediated Cardiac Lymphangiogenesis Promotes Inflammation Resolution in Autoimmune Acute Myocarditis in MiceSemantic proximity Read ↗

Endothelial cells adopt a pro-reparative immune responsive signature during cardiac injurySemantic proximity Read ↗

Single‐Cell RNA Sequencing Reveals the Temporal Diversity and Dynamics of Cardiac Immunity after Myocardial InfarctionSemantic proximity Read ↗

Activated T Lymphocytes are Essential Drivers of Pathological Remodeling in Ischemic Heart Failure.Semantic proximity Read ↗

Splenic CD169<sup>+</sup>Tim4<sup>+</sup>Marginal Metallophilic Macrophages Are Essential for Wound Healing After Myocardial InfarctionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.