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Article

Single‐Cell RNA Sequencing Reveals the Temporal Diversity and Dynamics of Cardiac Immunity after Myocardial Infarction

13 Jan 2022

Abstract excerpt

Abstract Myocardial infarction (MI) is strongly associated with the temporal regulation of cardiac immunity. However, a variety of current clinical trials have failed because of the lack of post‐MI immunomodulating/anti‐inflammatory targets. Single‐cell RNA sequencing analysis of the cardiac Cd45 + immune cell at 0, 3, 7, and 14 d after injury in a mouse left anterior descending coronary artery ligation model is...

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PMID: 35023642
DOI: 10.1002/smtd.202100752

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