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Single-Cell and Spatial Transcriptomics Identify Astrocyte Regulation of the Microenvironment and Prognosis in High-Grade Gliomas

2026-04-21

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> High-grade glioma is a highly malignant primary tumor of the central nervous system characterized by a poor clinical prognosis. The regulatory mechanisms of astrocytes within its TME are not fully understood. This study aimed to investigate the gene expression profiles, functional remodeling, prognostic significance, and regulatory role of astrocytes in the i...

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Literature Corpus work
67076132-1bf9-549f-a73a-6edd8f6b4eea
DOI
10.21203/rs.3.rs-9156282/v1
Open publication

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Single-Cell and Spatial Transcriptomics Identify Astrocyte Regulation of the Microenvironment and Prognosis in High-Grade GliomasDOI 10.21203/rs.3.rs-9156282/v1
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