Article
TagSNP approach for HLA risk allele genotyping of Saudi celiac disease patients: effectiveness and pitfalls.
Bioscience reports - 25 Jun 2021
Baaqeel Reham H, Banaganapalli Babajan, Al Mahdi Hadiah Bassam, Salama Mohammed A, Alhussaini Bakr H, Alaifan Meshari A, Bin-Taleb Yagoub, Shaik Noor Ahmad, Al-Aama Jumana Yousuf, Elango Ramu, Saadah Omar I
Abstract excerpt
BACKGROUND: Celiac disease (CD) is a genetically complex autoimmune disease which is triggered by dietary gluten. Human leukocyte antigen (HLA) class II genes are known to act as high-risk markers for CD, where >95% of CD patients carry (HLA), DQ2 and/or DQ8 alleles. Therefore, the present study was conducted to investigate the distribution of HLA haplotypes among Saudi CD patients and healthy controls by using...
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