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Article

In silico modeling of the interaction between TEX19 and LIRE1, and analysis of TEX19 gene missense SNPs.

Molecular genetics & genomic medicine - 1 Jul 2021

Alzahrani Faisal A, Hawsawi Yousef MohammedRabaa, Altayeb Hisham N, Alsiwiehri Naif O, Alzahrani Othman R, Alatwi Hanan E, Al-Amer Osama M, Alomar Suliman, Mansour Lamjed

Abstract excerpt

BACKGROUND: Testis expressed 19 (TEX19) is a specific human stem cell gene identified as cancer-testis antigen (CTA), which emerged as a potential therapeutic drug target. TEX19.1, a mouse paralog of human TEX19, can interact with LINE-1 retrotransposable element ORF1 protein (LIRE1) and subsequently restrict mobilization of LINE-1 elements in the genome. AIM: This study aimed to predict the interaction of TEX19...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34036740
DOI: 10.1002/mgg3.1707
PMCID: PMC8372073

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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