Article
Structural and biochemical insights into the role of testis-expressed gene 14 (TEX14) in forming the stable intercellular bridges of germ cells.
Proceedings of the National Academy of Sciences of the United States of America - 6 Oct 2015
Kim Hee Jung, Yoon Jungbin, Matsuura Atsushi, Na Jung-Hyun, Lee Won-Kyu, Kim Hyunook, Choi Ji Woong, Park Ji Eun, Park Sung-Jean, Kim Kyung Tae, Chang Rakwoo, Lee Byung Il, Yu Yeon Gyu, Shin Yeon-Kyun, Jeong Cherlhyun, Rhee Kunsoo, Lee Hyung Ho
Abstract excerpt
Intercellular bridges are a conserved feature of spermatogenesis in mammalian germ cells and derive from arresting cell abscission at the final stage of cytokinesis. However, it remains to be fully understood how germ cell abscission is arrested in the presence of general cytokinesis components. The TEX14 (testis-expressed gene 14) protein is recruited to the midbody and plays a key role in the inactivation of...
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