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Article

Multi-omics analysis of tumor mutational burden combined with prognostic assessment in epithelial ovarian cancer based on TCGA database.

International journal of medical sciences - 1 Jan 2020

Liu Jinhui, Xu Wei, Li Siyue, Sun Rui, Cheng Wenjun

Abstract excerpt

Background: Tumor mutation burden (TMB) is considered as a novel biomarker of response to immunotherapy and correlated with survival outcomes in various malignancies. Here, TMB-related genes (TRGs) expression signatures were constructed to investigate the association between TMB and prognosis in epithelial ovarian cancer (EOC), and the potential mechanism in immunoregulation was also explored. Methods: Based on...

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Source

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Identifiers

PMID: 33173439
DOI: 10.7150/ijms.50491
PMCID: PMC7646107

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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