Article
Disease-specific interactome alterations via epichaperomics: the case for Alzheimer's disease.
The FEBS journal - 1 Apr 2022
Ginsberg Stephen D, Neubert Thomas A, Sharma Sahil, Digwal Chander S, Yan Pengrong, Timbus Calin, Wang Tai, Chiosis Gabriela
Abstract excerpt
The increasingly appreciated prevalence of complicated stressor-to-phenotype associations in human disease requires a greater understanding of how specific stressors affect systems or interactome properties. Many currently untreatable diseases arise due to variations in, and through a combination of, multiple stressors of genetic, epigenetic, and environmental nature. Unfortunately, how such stressors lead to a...
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