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Article

Circulating Tumor DNA-Based Testing and Actionable Findings in Patients with Advanced and Metastatic Pancreatic Adenocarcinoma.

The oncologist - 1 Jul 2021

Botrus Gehan, Kosirorek Heidi, Sonbol Mohamad Bassam, Kusne Yael, Uson Junior Pedro Luiz Serrano, Borad Mitesh J, Ahn Daniel H, Kasi Pashtoon M, Drusbosky Leylah M, Dada Hiba, Surapaneni Phani Keerthi, Starr Jason, Ritter Ashton, McMillan Jessica, Wylie Natasha, Mody Kabir, Bekaii-Saab Tanios S

Abstract excerpt

PURPOSE: Recent advances in molecular diagnostic technologies allow for the evaluation of solid tumor malignancies through noninvasive blood sampling, including circulating tumor DNA profiling (ctDNA). Pancreatic ductal adenocarcinoma (PDAC) has a poor prognosis, often because of late presentation of disease. Diagnosis is often made using endoscopic ultrasound or endoscopic retrograde cholangiopancreatography,...

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Share to Adenocarcinoma
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Pancreatic Ductal

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Source

Open in PubMed Open full text

Identifiers

PMID: 33555095
DOI: 10.1002/onco.13717
PMCID: PMC8265372

Genes

KRAS
ATM
BRAF
CCND2
EGFR
MYC
PIK3CA
TP53

Variants

Provenance

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