Article
Detection of actionable mutations in cytological specimens obtained by endoscopic ultrasound-guided fine needle aspiration with rapid onsite evaluation in pancreatic cancer.
Annals of diagnostic pathology - 1 Oct 2022
Ohyama Hiroshi, Hirotsu Yosuke, Amemiya Kenji, Amano Hiroyuki, Hirose Sumio, Hosoda Kenji, Oyama Toshio, Iimuro Yuji, Kojima Yuichiro, Mikata Rintaro, Mochizuki Hitoshi, Kato Naoya, Omata Masao
Abstract excerpt
BACKGROUND: It is not clear whether archived cytological specimens (ACSs) obtained with endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) with rapid onsite evaluation (ROSE) can be used for genomic profiling of tumors. We used ACSs to perform genomic analysis of specimens to identify oncogenic and druggable mutations. METHODS: A panel of 60 significantly mutated genes specific to pancreatobiliary...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.