Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype.

doi:10.1158/1078-0432.CCR-17-0899

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Article

Real-Time Genomic Profiling of Pancreatic Ductal Adenocarcinoma: Potential Actionability and Correlation with Clinical Phenotype.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Oct 2017

Lowery Maeve A, Jordan Emmet J, Basturk Olca, Ptashkin Ryan N, Zehir Ahmet, Berger Michael F, Leach Tanisha, Herbst Brian, Askan Gokce, Maynard Hannah, Glassman Danielle, Covington Christina, Schultz Nikolaus, Abou-Alfa Ghassan K, Harding James J, Klimstra David S, Hechtman Jaclyn F, Hyman David M, Allen Peter J, Jarnagin William R, Balachandran Vinod P, Varghese Anna M, Schattner Mark A, Yu Kenneth H, Saltz Leonard B, Solit David B, Iacobuzio-Donahue Christine A, Leach Steven D, O'Reilly Eileen M

Abstract excerpt

Purpose: Molecular profiling in cancer has identified potential actionable drug targets that have prompted attempts to discover clinically validated biomarkers to guide therapeutic decision-making and enrollment to clinical trials. We evaluated whether comprehensive genetic analysis of patients with pancreatic adenocarcinoma is feasible within a clinically relevant timeframe and whether such analyses provide...

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PMID: 28754816
DOI: 10.1158/1078-0432.CCR-17-0899

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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