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Article

The variations in human orphan G protein-coupled receptor QRFPR affect PI3K-AKT-mTOR signaling.

Journal of clinical laboratory analysis - 1 Jul 2021

Li Huanzheng, Lou Ran, Xu Xueqin, Xu Chenyang, Yu Yuan, Xu Yunzhi, Hu Lin, Xiang Yanbao, Lin Xuan, Tang Shaohua

Abstract excerpt

BACKGROUND: QRFPR is a recently identified member of the G protein-coupled receptor and is an orphan receptor for 26Rfa, which plays important role in the regulation of many physiological functions. METHODS: Here, we employed whole exome sequencing (WES) to examine the patients with intellectual disability (ID) and difficulty in feeding. We performed SIFT and PolyPhen2 predictions for the variants. The structure...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34018631
DOI: 10.1002/jcla.23822
PMCID: PMC8275006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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