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Improved epidermal barrier formation in human skin models by chitosan modulated dermal matrices

23 Mar 2017

Abstract excerpt

Full thickness human skin models (FTMs) contain an epidermal and a dermal equivalent. The latter is composed of a collagen dermal matrix which harbours fibroblasts. Current epidermal barrier properties of FTMs do not fully resemble that of native human skin (NHS), which makes these human skin models less suitable for barrier related studies. To further enhance the resemblance of NHS for epidermal morphogenesis...

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Advancements in Transdermal Drug Delivery
Dermatology and Skin Diseases
Skin Protection and Aging

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28333992
DOI: 10.1371/journal.pone.0174478

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