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Nature versus nurture: does human skin maintain its stratum corneum lipid properties <i>in vitro</i>?

24 Sept 2012

Abstract excerpt

Human skin equivalents (HSEs) mimic human skin closely, but show differences in their stratum corneum (SC) lipid properties. The aim of this study was to determine whether isolation of primary cells, which is needed to generate HSEs, influence the SC lipid properties of HSEs. For this purpose, we expanded explants of intact full thickness human skin and isolated epidermal sheets in vitro. We investigated whether...

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PMID: 23163653
DOI: 10.1111/exd.12031

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