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Article

Barrier Properties of an N/TERT-Based Human Skin Equivalent

13 May 2014

Abstract excerpt

Human skin equivalents (HSEs) can be considered a valuable tool to study aspects of human skin, including the skin barrier, or to perform chemical or toxicological screenings. HSEs are three-dimensional skin models that are usually established using primary keratinocytes and closely mimic human skin. The use of primary keratinocytes has several drawbacks, including a limited in vitro life span and large...

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PMID: 24819925
DOI: 10.1089/ten.tea.2014.0011

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