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An <i>ex vivo human</i> skin model for studying skin barrier repair

3 Nov 2014

Abstract excerpt

In the studies described in this study, we introduce a novel ex vivo human skin barrier repair model. To develop this, we removed the upper layer of the skin, the stratum corneum (SC) by a reproducible cyanoacrylate stripping technique. After stripping the explants, they were cultured in vitro to allow the regeneration of the SC. We selected two culture temperatures 32 °C and 37 °C and a period of either 4 or 8...

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PMID: 25363465
DOI: 10.1111/exd.12579

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