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Article

Modifying chromatin and concepts of cancer.

Current opinion in genetics & development - 1 Apr 1999

Jacobson S, Pillus L

Abstract excerpt

A wave of biochemical and genetic progress has identified proteins that influence transcription by modifying chromatin. Many such factors are broadly conserved and, strikingly, occur in human diseases as partners in chromosomal translocations. Understanding the function of these factors will be k...

Topics

Acetyltransferases
Animals
Artificial Gene Fusion
Chromatin
DNA-Binding Proteins
Histone Acetyltransferases
Histone-Lysine N-Methyltransferase
Humans
Mutation
Myeloid-Lymphoid Leukemia Protein
Neoplasms
Nuclear Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogenes

Trans-Activators

Transcription Factors

Transcription, Genetic

Source

Identifiers

PMID: 10322138
DOI: 10.1016/S0959-437X(99)80027-6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026. Prepared record publication-10322138-2026-08-31.1. Manifest publication-graph-cohort-2026-08-31.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 31 Aug 2026.

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