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Identification and validation of ferroptosis-related genes and immune cell infiltration in thyroid associated ophthalmopathy

20 Mar 2023

Abstract excerpt

Thyroid associated ophthalmopathy (TAO) is an orbital autoimmune inflammatory disease that is commonly associated with thyroid dysfunction. Although the etiology of TAO is unclear, ROS accumulation and oxidative stress have been closely linked to the pathogenesis of TAO. Ferroptosis is an iron-dependent programmed cell death characterized by intracellular labile iron levels, excessive accumulation of reactive...

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PMID: 37021001
DOI: 10.3389/fgene.2023.1118391

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