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Article

Identifying expression and DNA methylation biomarkers for lung adenocarcinoma risk in East Asia.

Journal of the National Cancer Institute - 1 Jun 2026

Chen Tzu-Yu, Chien Li-Hsin, Jiang Shih Sheng, Choi Jiyeon, Hung Hsiao-Han, Hsiao Chin-Fu, Shi Jianxin, Blechter Batel, Breeze Charles E, Chang Gee-Chen, Chen Kuan-Yu, Tsai Ying-Huang, Su Wu-Chou, Huang Ming-Shyan, Chen Yuh-Min, Wen Yueh-Feng, Chen Chung-Yu, Wang Chih-Liang, Tsai Fang-Yu, Chen Hui-Ling, Hsieh Wan-Shan, Lin Hsien-Chih, Wang Lu-Hai, Chen Chien-Jen, Yang Pan-Chyr, Chen Chih-Yi, Rothman Nathaniel, Chanock Stephen J, Lan Qing, Chang I-Shou, Hsiung Chao A

Abstract excerpt

BACKGROUND: Lung adenocarcinoma (LUAD) is the most common type of lung cancer. A recent genome-wide association study of lung adenocarcinoma in East Asia reported 28 independent susceptibility variants across 25 loci and identified 2 genes whose genetically predicted expression levels are associated with lung adenocarcinoma risk, using an ancestry-matched lung tissue expression quantitative trait loci (QTL)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41581221
DOI: 10.1093/jnci/djag021
PMCID: PMC13247344

Genes

CCDC116
DSP
ELF5
GSDMB
IKZF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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