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Article

KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice.

PLoS genetics - 1 May 2021

Oura Seiya, Koyano Takayuki, Kodera Chisato, Horisawa-Takada Yuki, Matsuyama Makoto, Ishiguro Kei-Ichiro, Ikawa Masahito

Abstract excerpt

Meiosis is a cell division process with complex chromosome events where various molecules must work in tandem. To find meiosis-related genes, we screened evolutionarily conserved and reproductive tract-enriched genes using the CRISPR/Cas9 system and identified potassium channel tetramerization domain containing 19 (Kctd19) as an essential factor for meiosis. In prophase I, Kctd19 deficiency did not affect...

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Identifiers

PMID: 33961623
DOI: 10.1371/journal.pgen.1009412
PMCID: PMC8104389

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice.PMID 33961623Read ↗

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