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Article

Gene dosage changes in <i>KCTD13</i> result in penile and testicular anomalies via diminished androgen receptor function

5 Oct 2022

Abstract excerpt

Despite the high prevalence of hypospadias and cryptorchidism, the genetic basis for these conditions is only beginning to be understood. Using array-comparative-genomic-hybridization (aCGH), potassium-channel-tetramerization-domain-containing-13 (KCTD13) encoded at 16p11.2 was identified as a candidate gene involved in hypospadias, cryptorchidism and other genitourinary (GU) tract anomalies. Copy number variants...

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Identifiers

PMID: 36196997
DOI: 10.1096/fj.202200558r

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