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Article

RNF216 regulates meiosis and PKA stability in the testes

16 Mar 2021

Abstract excerpt

Abstract Spermatogenesis is a highly sophisticated process that comprises of mitosis, meiosis, and spermiogenesis. RNF216 (ring finger protein 216), an E3 ubiquitin ligase, has been reported to be essential for spermatogenesis and male fertility in mice. However, the stages affected by Rnf216 deficiency and its underlying molecular pathological mechanisms are still unknown. In this study, we generated Rnf216...

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PMID: 33724554
DOI: 10.1096/fj.202002294rr

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