Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Immune Reconstitution in the Aging Host: Opportunities for Mechanism-Based Therapy in Allogeneic Hematopoietic Cell Transplantation

19 Apr 2021

Abstract excerpt

Older patients with hematologic malignancies are increasingly considered for allogeneic hematopoietic cell transplantation with encouraging outcomes. While aging-related thymic dysfunction remains a major obstacle to optimal and timely immune reconstitution post- transplantation, recent accumulating evidence has suggested that various aging hallmarks such as cellular senescence, inflamm-aging, and hematopoietic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Hematopoietic Stem Cell Transplantation
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33953731
DOI: 10.3389/fimmu.2021.674093

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Immune Reconstitution in the Aging Host: Opportunities for Mechanism-Based Therapy in Allogeneic Hematopoietic Cell TransplantationPMID 33953731Read ↗

Immune aging: biological mechanisms, clinical symptoms, and management in lung transplant recipientsSemantic proximity Read ↗

Causes and Mechanisms of Hematopoietic Stem Cell AgingSemantic proximity Read ↗

Concise review: hematopoietic stem cell aging, life span, and transplantation.Semantic proximity Read ↗

Reconsidering the usual suspects in age-related hematologic disorders: is stem cell dysfunction a root cause of aging?Semantic proximity Read ↗

Graft versus Host Disease: From Basic Pathogenic Principles to DNA Damage Response and Cellular SenescenceSemantic proximity Read ↗

The aging hematopoietic stem cell niche: Phenotypic and functional changes and mechanisms that contribute to hematopoietic aging.Semantic proximity Read ↗

Molecular and cellular mechanisms of aging in hematopoietic stem cells and their niches.Semantic proximity Read ↗

Mechanisms of immunosenescence: lessons from models of accelerated immune agingSemantic proximity Read ↗

Immunosenescence promotes cancer development: from mechanisms to treatment strategiesSemantic proximity Read ↗

The ageing haematopoietic stem cell compartment.Semantic proximity Read ↗

Cellular and Molecular Mechanisms Involved in Hematopoietic Stem Cell Aging as a Clinical ProspectSemantic proximity Read ↗

Characteristics and mechanisms of T‐cell senescence: A potential target for cancer immunotherapySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.