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Cellular and Molecular Mechanisms Involved in Hematopoietic Stem Cell Aging as a Clinical Prospect

1 Jan 2022

Abstract excerpt

There is a hot topic in stem cell research to investigate the process of hematopoietic stem cell (HSC) aging characterized by decreased self‐renewal ability, myeloid‐biased differentiation, impaired homing, and other abnormalities related to hematopoietic repair function. It is of crucial importance that HSCs preserve self‐renewal and differentiation ability to maintain hematopoiesis under homeostatic states over...

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PMID: 35401928
DOI: 10.1155/2022/2713483

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