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Article

Graft versus Host Disease: From Basic Pathogenic Principles to DNA Damage Response and Cellular Senescence

1 Jan 2018

Abstract excerpt

Graft versus host disease (GVHD), a severe immunogenic complication of allogeneic hematopoietic stem cell transplantation (HSCT), represents the most frequent cause of transplant-related mortality (TRM). Despite a huge progress in HSCT techniques and posttransplant care, GVHD remains a significant obstacle in successful HSCT outcome. This review presents a complex summary of GVHD pathogenesis with focus on...

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Identifiers

PMID: 29785172
DOI: 10.1155/2018/9451950

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