Article
NAMPT single-nucleotide polymorphism rs1319501 and visfatin/NAMPT affect nitric oxide formation, sFlt-1 and antihypertensive therapy response in preeclampsia.
Pharmacogenomics - 1 Jun 2021
Pereira Daniela A, Sandrim Valeria C, Palei Ana C, Amaral Lorena M, Belo Vanessa A, Lacchini Riccardo, Cavalli Ricardo C, Tanus-Santos Jose E, Luizon Marcelo R
Abstract excerpt
Aim: We examined the relationships between visfatin/NAMPT and nitrite concentrations (a marker of nitric oxide [NO] formation) or sFlt-1 levels in 205 patients with preeclampsia (PE) responsive or nonresponsive to antihypertensive therapy, and whether NAMPT SNPs rs1319501 and rs3801266 affect nitrite concentrations in PE and 206 healthy pregnant women. Patients & methods: Circulating visfatin/NAMPT and sFlt-1...
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