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Article

Effects of arginase genetic polymorphisms on nitric oxide formation in healthy pregnancy and in preeclampsia.

Nitric oxide : biology and chemistry - 1 May 2021

Pinto-Souza Caroline C, Coeli-Lacchini Fernanda, Luizon Marcelo R, Cavalli Ricardo C, Lacchini Riccardo, Sandrim Valeria C

Abstract excerpt

BACKGROUND AND AIMS: Preeclampsia is associated with reduced nitric oxide (NO) bioavailability. Arginase is related to NO synthesis, but relatively unexplored in preeclampsia. However, no previous study has examined whether variations in ARG1 and ARG2 genes affect NO bioavailability and the risk of preeclampsia. Here, we compared the alleles and genotypes of single nucleotide polymorphisms (SNPs) in ARG1...

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Source

Identifiers

PMID: 33676021
DOI: 10.1016/j.niox.2021.02.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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