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Maternal miRNA-146a G/C rs2910164 variation, HIV/AIDS and nitrogen oxide pollution exposure collectively affects foetal growth.

Human & experimental toxicology - 1 Jan 2019

Naidoo P, Naidoo R N, Ramkaran P, Muttoo S, Asharam K, Chuturgoon A A

Abstract excerpt

OBJECTIVE:: Nitrogen oxide (NOx) pollution and human immunodeficiency virus (HIV)/AIDS intensify inflammation during pregnancy and linked with adverse birth outcomes (ABOs). MicroRNA (miRNA)-146a plays a crucial role in regulating inflammation in the NF-κB pathway. The G/C rs2910164 dampens miRNA-146a activity and linked with inflammatory diseases. The present study investigated whether HIV/AIDS and NOx exposure...

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Air Pollutants
Environmental Exposure
Fetal Development
HIV Infections

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Infant, Low Birth Weight

Premature Birth

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PMID: 29896975
DOI: 10.1177/0960327118781902

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ABO

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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