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Article

NAMPT (visfatin) and AKT1 genetic variants associate with myocardial infarction.

Clinica chimica acta; international journal of clinical chemistry - 11 Apr 2012

Leander Karin, Gigante Bruna, Silveira Angela, Vikström Max, Hamsten Anders, Högberg Johan

Abstract excerpt

BACKGROUND: High plasma levels of the adipokine NAMPT (or visfatin) have been associated with cardiovascular disease. However experimental data suggest that NAMPT, via Akt signaling, protects the myocardium against hypoxic insults. We studied whether the NAMPT rs1319501, AKT1 rs3730358, p53 rs1042522, Mdm2 rs2279744 or eNOS rs1799983 SNP:s linked to NAMPT and Akt signaling associate with risk of myocardial...

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Share to Myocardial Infarction
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Share to Polymorphism, Single Nucleotide
Share to Proto-Oncogene Proteins c-akt

Source

Identifiers

PMID: 22251423
DOI: 10.1016/j.cca.2012.01.002

Genes

NAMPT
AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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NAMPT (visfatin) and AKT1 genetic variants associate with myocardial infarction.PMID 22251423Read ↗

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