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Article

Sortilin as a Biomarker for Cardiovascular Disease Revisited

16 Apr 2021

Abstract excerpt

Genetic variants in the genomic region containing SORT1 (encoding the protein sortilin) are strongly associated with cholesterol levels and the risk of coronary artery disease (CAD). Circulating sortilin has therefore been proposed as a potential biomarker for cardiovascular disease. Multiple studies have reported association between plasma sortilin levels and cardiovascular outcomes. However, the findings are...

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Identifiers

PMID: 33937362
DOI: 10.3389/fcvm.2021.652584

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