Article
Transcription Factor Evaluation by Flow Cytometry.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Fenoglio Daniela, Altosole Tiziana
Abstract excerpt
The development of T helper (Th) cell subsets requires activated T cells that respond to a polarizing cytokine environment, resulting in the activation and expression of specific transcription factors. The subset-specific transcription factors are located either in the cytoplasm or in the nucleus, which determine the functional profile of Th populations, inducing the production of specific effector cytokines and...
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