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Article

Functional and genomic analyses of FOXP3-transduced Jurkat-T cells as regulatory T (Treg)-like cells.

Biochemical and biophysical research communications - 12 Oct 2007

Kim Joon-Young, Kim Han-Jong, Hurt Elaine M, Chen Xin, Howard O M Zack, Farrar William L

Abstract excerpt

FOXP3, a forkhead transcription factor is essential for the development and function of CD4(+)CD25(+) regulatory T cells (Tregs). In contrast to conversion of murine naive T cells to Tregs by transduction of Foxp3, it is controversial whether ectopic expression of FOXP3 in human CD4(+) T cells is...

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Source

Identifiers

PMID: 17706604
DOI: 10.1016/j.bbrc.2007.07.187

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17706604-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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