Article
Cell surface markers for immunophenotyping human pluripotent stem cell-derived cardiomyocytes.
Pflugers Archiv : European journal of physiology - 1 Jul 2021
Boheler Kenneth R, Poon Ellen Ngar-Yun
Abstract excerpt
Human pluripotent stem cells (hPSC) self-renew and represent a potentially unlimited source for the production of cardiomyocytes (CMs) suitable for studies of human cardiac development, drug discovery, cardiotoxicity testing, and disease modelling and for cell-based therapies. However, most cardiac differentiation protocols yield mixed cultures of atrial-, ventricular-, and pacemaker-like cells at various stages...
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